Long-Term Monitoring of Liver Fibrosis and Steatosis in Patients with Chronic Hepatitis C after Achieving a Sustained Virologic Response to Antiviral Therapy

Aim: to analyze the dynamics of fibrosis and steatosis liver according fibroelastometry in patients with chronic hep-atitis C (CHC) after ≥ 6 months from transient elastometry (TE) achieving a sustained virologic response (SVR) antiviral therapy. Materials methods. At baseline, prospective observational study included 628 CHC known stage (F) before AVT, some whom were phased out due non-compliance inclusion criteria. The final analysis 297 who had data CAP™ technology on severity (± steatosis) treatment reaching SVR (67 % – interferonfree regimens therapy). Median follow-up moment was confirmed 3 years [2; 6]. Results. end study, average age 49 ± 12 years, which 53 men. In long-term period SVR, regression diagnosed 80 cases (including cirrhosis), progression patient. same time, detected only 31 patient, worsening results 23 (26 them appearance (S) 1–3 degrees persons no fatty start AVT). group steatosis, proportion men significantly higher ( p = 0.004). Clinically significant stages F3–F4 more often recorded hepatic both (46 S1–S3 22 S0, < 0.001) (19 9 0.023). Conclusion. hepatitis achieved long term, despite fibrosis, high prevalence remains. obtained indicate feasibility routine diagnosis management HCV infection successful